12 Popular Weight Loss Pills and Supplements Reviewed

Do any weight loss pills really work?

When it comes to weight loss, there is no shortage of pills, drinks, and supplements claiming to help the weight fall off. But do weight loss pills help, and are they safe?
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The best weight loss pills may contain one or more active ingredients intended to increase fat burning, decrease appetite, or reduce absorption of fat.
Not all weight loss pills and supplements are created equal. Certain pills may cause unpleasant side effects while others may not be proven to result in weight loss.
We will look at the following nine weight loss pills and supplements:
  • Alli (orlistat)
  • caffeine
  • glucomannan
  • garcinia cambogia extract
  • pyruvate
  • green tea extract
  • conjugated linoleic acid
  • Hydroxycut
  • prescription weight loss pills

1. Alli (orlistat)

There are many different weight loss solutions out there.
This includes all sorts of pills, drugs and natural supplements.
These are claimed to help you lose weight, or at least make it easier to lose weight combined with other methods.
They tend to work via one or more of these mechanisms:
  1. Reduce appetite, making you feel more full so that you eat fewer calories
  2. Reduce absorption of nutrients like fat, making you take in fewer calories
  3. Increase fat burning, making you burn more calories
Here are the 12 most popular weight loss pills and supplements, reviewed by science.
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1. Garcinia Cambogia Extractarcinia cambogia became popular worldwide after being featured on the Dr. Oz show in 2012.
It is a small, green fruit, shaped like a pumpkin.
The skin of the fruit contains hydroxycitric acid (HCA). This is the active ingredient in garcinia cambogia extract, which is marketed as a diet pill.
How it works: Animal studies show that it can inhibit a fat-producing enzyme in the body and increase levels of serotonin, potentially helping to reduce cravings (12).
Effectiveness: One study with 130 people compared garcinia against a dummy pill. There was no difference in weight or body fat percentage between groups (3).
A 2011 review that looked at 12 studies on garcinia cambogia found that, on average, it caused weight loss of about 2 pounds (0.88 kg) over several weeks (4).
Side effects: There are no reports of serious side effects, but some reports of mild digestive problems

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